Promoter Region Of Genes

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Promoter (genetics) - Wikipedia

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In genetics, a promoter is a sequence of DNA to which proteins bind that initiate transcription of a single RNA from the DNA downstream of it. This RNA may encode a protein, or can have a function in and of itself, such as tRNA, mRNA, or rRNA.Promoters are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense strand).

Actived: Thursday Nov 19, 2020

Link: https://en.wikipedia.org/wiki/Promoter_(genetics)

Addgene: Promoters

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A promoter is a region of DNA where transcription of a gene is initiated. Promoters are a vital component of expression vectors because they control the binding of RNA polymerase to DNA. RNA polymerase transcribes DNA to mRNA which is ultimately translated into a functional protein. Thus the promoter region controls when and where in the organism your gene of interest is expressed. Summary

Actived: Saturday Nov 21, 2020

Link: https://www.addgene.org/mol-bio-reference/promoters/

Promoter - Genome.gov

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The promoter region is the sequence typically referred to that's right upstream or right next to where a gene is about to be transcribed. It's the region where certain regulatory elements will bind; these are proteins that will bind to help RNA get transcribed.

Actived: Thursday Nov 19, 2020

Link: https://www.genome.gov/genetics-glossary/Promoter

Gene Promoter - an overview | ScienceDirect Topics

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Albertha J.M. Walhout, in Methods in Cell Biology, 2011. 1 Promoters. A gene promoter is the genomic DNA sequence immediately upstream of the transcription start site. Generally, promoters are composed of a basal element where the general transcriptional machinery binds (e.g., RNA polymerase II and general TFs), and the proximal gene promoter that serves as a landing site for regulatory TFs.

Actived: Friday Nov 13, 2020

Link: https://www.sciencedirect.com/topics/medicine-and-dentistry/gene-promoter

Human gene on/off switches to be mapped | New Scientist

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Promoter region. Methylation is a natural process that mainly occurs on cytosine, one of the four “letters” or bases that make up DNA. When a methyl group is added on to cytosine in the

Actived: Monday Oct 26, 2020

Link: https://www.newscientist.com/article/dn4241-human-gene-onoff-switches-to-be-mapped/

promoter region of gene

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I plan to compare the promoter region of same genes in pan-genome (a set of genomes of different enhancer annotation for mouse mm9 . I found a promoter, gene body, transcript, exons annotation via TxDb.Mmusculus.UCSC.mm9.knownGene Is There A Better Promoter Annotation Than Just Taking The 5-Prime Ends Of Ucsc Known Genes"? I am looking at ChIP-seq data by comparing read counts in

Actived: Tuesday Nov 3, 2020

Link: https://www.biostars.org/p/298528/

How to locate promoter sequence for a specific gene

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Here is the BRCA2 promoter sequence aligned to BRAC2 gene. In UCSC genome broswer, you can turn on CpG island feature, if there is CpG island in the promoter sequence, the sequence is highly likely a true promoter. In the above example (BRCA2), a CpG island is displayed in the proximal promoter. Beware some genes have alternative promoters. To

Actived: Friday Nov 20, 2020

Link: https://signagen.com/blog/2015/10/14/how-to-locate-promoter-sequence-for-a-specific-gene/

DNA methylation - Wikipedia

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They are major regulatory units and around 50% of CpG islands are located in gene promoter regions, while another 25% lie in gene bodies, often serving as alternative promoters. Reciprocally, around 60-70% of human genes have a CpG island in their promoter region.

Actived: Friday Nov 20, 2020

Link: https://en.wikipedia.org/wiki/DNA_methylation

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